STAFF

Dr. Ángel Nadal Navajas

Professor of Physiology, Universidad Miguel Hernandez

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Unit
Physiology

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nadal@umh.es

+34 96 522 2002

RESEARCH FIELDS 

  • We work to understand the role that estrogen receptors ERα, ERβ and GPER1 have in the physiology of the islet of Langerhans. This will give light on how estrogens influence the plasticity of the endocrine pancreas during the adaptation to pregnancy and obesity. We are interested in the role that endocrine disruptors, particularly those with estrogenic activity, have in the etiology of Diabetes.

PROFESSIONAL BACKGROUND

  • Previous positions:
  • Postdoctoral positions:
  • PhD in
  • Degree in …

REPRESENTATIVE PUBLICATIONS

García-Arevalo M., et al. (2014)

PLoS One, DOI: 10.1371/journal.pone.0100214

Exposure to Bisphenol-A during Pregnancy Partially Mimics the Effects of a High-Fat Diet Altering Glucose Homeostasis and Gene Expression in Adult Male Mice.

Alonso-Magdalena P., et al. (2013)

Diabetes, DOI: 10.2337/db12-1562

Antidiabetic actions of an ERβ selective agonist.

Soriano S., et al. (2012)

PLoS One, DOI: 10.1371/journal.pone.0031109

Rapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor beta

Alonso-Magdalena P., et al. (2011)

Nature Reviews Endocrinology, DOI: 10.1038/nrendo.2011.56

Endocrine disruptors in the etiology of type 2 diabetes mellitus.

Alonso-Magdalena P., et al. (2010)

Environmental Health Perspectives, DOI: 10.1289/ehp.1001993

Homeostasis in Mothers and Adult Male Offspring.

PATENTS AND AVAILABLE TECHNOLOGIES

Utilización del 17beta-estradiol, sus análogos y derivados en el tratamiento de la diabetes mellitus y sus manifestaciones

Inventors: B. Soria, A. Nadal, C. Ripoll, J.M. Rovira, E. Andreu, O. Laribi y T. León-Quinto.
Number: P9800625.
 
Date: 24 de marzo 1998
Countries: Spain