STAFF

Dr. Antonio Vicente Ferrer Montiel

Professor of Biochemistry and Molecular Biology, Universidad Miguel Hernandez

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Unit
Molecular and Cellular Design

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Subunit
Molecular Recognizement and Protein Engineering

Group
Sensory Neurobiology

aferrer@umh.es

+ 34 966 65 87 27

RESEARCH FIELDS 

  • Sensory neurobiology with a focus on molecular and cellular mechanisms of pain transduction
  • Discovery and development of anti-nociceptive drugs.
  • Structure-function studies on thermo-sensory ion channels.

PROFESSIONAL BACKGROUND

  • Previous positions:
    1. Fellowship from the Ministry of Health, Universidad de Alicante, Spain, 1986-1989.
    2. Postdoctoral fellowship from the Ministry of Education, University of California San Diego, 1990-1992.
    3.-Postdoctoral fellowship from NATO, University of California San Diego, 1993.
    4. Postgraduate Researcher, University of California San Diego, 1994-1996.
    5.-Assistant Project Scientist Step II; Dept. Biology, UCSD, USA. 1996.
    6.-Assistant Project Scientist Step III. Dept. Biology, UCSD, USA. 1997.
    7.-Assistant Professor of Biochemistry and Molecular Biology (Tenure-Track). University Miguel Hernández (UMH), Spain. 1999.
    8.-Associate Professor (Tenure), UMH, Spain. 1999-2007.
    9.-Full Professor, UMH, Spain. 2007-present.
    10.-Director, Institute of Molecular and Cellular Biology, 2012-present.

  • Postdoctoral positions:
    1. Department of Physics, University of California San Diego, 1990-1993.
    2. Department of Biology, Universitsy of California San Diego, 1993-1997.
  • PhD programme: 
    1.-Molecular Neurosciences, Institute of Neurosciences, Universidad de Alicante,1989 (Director: Prof. José A. Ferragut)
    2.-Awarded the Prize to the Best Thesis, Universidad de Alicante, 1990.
  • Degree in Chemistry.

REPRESENTATIVE PUBLICATIONS

Devesa, I., et al. (2014)

Proceedings of the National Academy of Sciences of the United States of America, DOI: 10.1073/pnas.1420252111

Alpha-CGRP is essential for pro-algesic sensitization of TRPV1 in peptidergic C-type nociceptors.

Taberner, F., et al. (2014)

The Journal of Biological Chemistry, DOI: 10.1074/jbc.M114.577478

The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation

Bonache, M.A., et al. (2014)

ACS Combinatorial Science, DOI: 10.1021/co500005x

De novo design, synthesis, structure and validation of a library of helical peptides for modulation of protein-protein interactions.

Gregorio-Teruel, L., et al. (2014)

The Journal of General Physiology, DOI:10.1085/jgp.201311070

Mutation of I696 and W697 in the trp box of vanilloid receptor subtype modulate allosteric channel activation

Devesa I. and Ferrer-Montiel A. (2014)

The European Journal of Neuroscience, DOI: 10.1111/ejn.12455

Neurotrophins, endocannabinoids and thermoTRPs: a threesome in pain signalings.

PATENTS AND AVAILABLE TECHNOLOGIES

Neuronal exocytosis inhibiting peptide and cosmetic composition and pharmaceutical composition containing the peptide

Inventores: Blanes C, Llobregat M, Gil A, Fernández-Ballester G, Planells Cases R, Viniegra S, Gutierrez LM, Carbonell T, Pérez-Payá E, Ferrer-Montiel. A.
Nº : ES2160482 B1 (granted on 18/04/2002); EP1180524 B1 (granted on 30/08/2006); CA2370289 A1; US7015192 B1 (granted on 21/03/2006); US77473679 B1 (granted on 21/03/2006).

N-alkylglycine trimeres capable of blocking the response to chemical substances, thermal stimuli or mediators of neuronal receptor inflammation and compositions containing said trimeres

Inventores: Antonio Ferrer Montiel, Asia Fernández Carvajal, Carolina García Martínez, Carlos Belmonte Martínez, Wim van den Nest, Cristina Carreño Serraima.
Nº: ES2169691 B1 (granted on 16/03/2004); WO02/30956; EP1338605 A1; US2004/33958; AU9388201; BR200114802 A; CA2425520 A1; JP2004/511491; MX PA/a/03003158.

 

N-alkylglycine trimeres capable of protecting neurons against excitotoxic aggressions and compositions containing such trimeres

Inventores: Felipo V, Montoliu C, Planells Cases R, Merino J, Pérez-Payá E, Sánchez-Baeza F, Humet M, Messeguer A, Ferrer-Montiel, A.
Nº : ES2169690 B1 (granted on 16/03/2004); ES2267816 T3 (granted on 16/03/2007); WO02/28885; EP1338604 B1 (granted on 12/07/2006); US6992064 B1 (granted on 31/01/2006); AU2001291906 A; BRPI0114660 A; CA2427072 A1; JP2002-532467; KR 849739 (granted on 01/08/2008); MX244057 B (granted on 09/03/2007).

Compounds which can block the responses to chemical substances or thermal stimuli or mediators of inflammation of nociceptors, production method thereof and compositions containing same

Inventores: Fernández-Carvajal A, García-Martínez C, Belmonte C, Van Den Nest W, Carreño C., Ferrer-Montiel A.
Nº: ES2195787 B1 (granted on 01/06/2005); WO03/097670; EP1506970 A1; US7183430 B2 (granted on 27/02/2003); AU2003/231331; CA2486342 A1; JP2006/502975 ; MX PA/a/04011502.

Dermopharmaceutical or cosmetic composition comprising enkephaline-derived peptides for reducing and/or eliminating facial wrinkles

Inventores: Ferrer-Montiel A, Cebrián J, Puig A.
Nº: ES2259928 B1 (granted on 06/09/2007); WO2006/106164; EP1892247 A1; US11/910719; AU2006231273; BR 0609745-6; CA2608165 A1; JP2008-504786; MX PA/a/2007012504.
 

COMPANY AGREEMENTS

  • BCN Peptides
  • DiverDrugs