Dr. Asia Fernández Carvajal

Professor of Biochemistry and Molecular Biology, Universidad Miguel Hernandez


Molecular Diagnosis and Therapy


Bioactive Molecules

Pain Signaling: Design of Drugs on TRP Receptors

+ 34 966 65 84 54


  • High throughput screening.
  • Discovery and development of anti-nociceptive drugs.
  • Structure-function studies on ion channels.


  • Previous positions:
    1. 1988-1991: Predoctoral Fellowship from M.E.C.: Department of Neurochemistry. Medicine Faculty University of Alicante.
    2. 1992-1995: Postdoctoral Fellowship from European Comunity. Investigation in Neuroreceptors and ionic channels.
    3. 1988-1997: Lecturer in Biochemistry. Department of Neurochemistry. Medicine Faculty. University of Alicante.
    4. 1997-2009: Assistant Profesor of Enzimology and Biochemistry. Department of Biochemistry and molecular. UMH University.
  • Postdoctoral positions:  
  • PhD in
  • Degree in Biology.


Serafini M., et al. (2018)

Journal of Medicinal Chemistry, DOI: 10.1021/acs.jmedchem.8b00109

Targeting TRPV1 softly: the discovery of Passerini adducts as a topical treatment for inflammatory skin disorders. Journal of Medicinal Chemistry.

Balsera, B., et al. (2018)

European Journal of Medicinal Chemistry, DOI: 10.1016/j.ejmech.2017.10.083

Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of α7 nicotinic receptors with analgesic activity.

Torre-Martínez, R., et al. (2017)

Scientific Reports, DOI: 10.1038/s41598-017-10913-x

Synthesis, high-throughput screening and pharmacological characterization of β-lactam derivatives as TRPM8 antagonists.

Montoya E., et al. (2017)

Biochimica et Biophysica Acta, DOI: 10.1016/j.bbamem.2017.01.014

Differential binding of monovalent cations to KcsA: Deciphering the mechanisms of potassium channel selectivity.

Bertaminoa A., et al.(2016)

Journal of Medicinal Chemistry, DOI: 10.1021/acs.jmedchem.5b01914

Tryptamine-based derivatives as Transient Receptor Potential Melastatin type-8 (TRPM8) channel modulators.


Compounds which can block the responses to chemical substances or thermal stimuli or mediators of inflammation of nociceptors, production method thereof and compositions containing same

Inventores: Fernández-Carvajal A, García-Martínez C, Belmonte C, Van Den Nest W, Carreño C., Ferrer-Montiel A.
Titular: Universidad Miguel Hernández.
Nº : ES2195787 B1 (granted on 01/06/2005); WO03/097670; EP1506970 A1; US7183430 B2 (granted on 27/02/2003); AU2003/231331; CA2486342 A1; JP2006/502975 ; MX PA/a/04011502.

New bis-N-(halophenethyl)-glycyl-glycine derivatives, useful as analgesic medicaments, especially for treating inflammatory or neuropathic pain, or in cosmetic compositions

Inventores: Antonio Ferrer Montiel, Asia Fernández Carvajal, Carolina García Martínez, Carlos Belmonte Martínez, Wim van den Nest, Cristina Carreño Serraima.
Titular: University of Groningen; EMBL; National University of Ireland.
Nº: WO2003097670-A; WO2003097670-A1; ES2195787-A1; AU2003231331-A1; EP1506970-A1; KR2005007406-A; ES2195787-B1; US2005130907-A1; JP2006502975-W; US7183430-B2.

Pharmaceutical composition for the treatment of the dry eye

Inventores: Carlos Belmonte Martínez, Juana Gallar Martinez, Antonio Ferrer Montiel, Asia Fernández Carvajal, Felix Viana de la Iglesia.
Nº: WO2012/032209 A2 EP2614860A2, EP2614860A4, US20130245231, WO2012032209A3.


  • BCN Peptides
  • DiverDrugs